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Erschienen in: Wiener Medizinische Wochenschrift 17-18/2014

01.09.2014 | review

Bullöses Pemphigoid – Diagnostik und Therapie

verfasst von: Dr. med. Andrea Kneisel, Prof. Dr. med. Michael Hertl

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 17-18/2014

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Zusammenfassung

Das bullöse Pemphigoid ist die häufigste blasenbildende Autoimmundermatose und kommt vor allem im höheren Lebensalter vor. Klinisch zeigen sich pralle Blasen und ekzematöse Hautveränderungen bei starkem Juckreiz. Die Gruppe der Pemphigoiderkrankungen umfasst z. B. Schleimhautpemphigoid, Pemphigoid gestationis und lineare IgA-Dermatose. Die Diagnosestellung erfolgt durch Immunfluoreszenzuntersuchungen sowie Bestätigungstests (ELISA, Immunoblot). Das klassische bullöse Pemphigoid weist IgG-Autoantikörper gegen BP180 sowie BP230 auf. Therapeutisch werden topische und ggf. systemische Kortikosteroide und adjuvante Immunsuppressiva eingesetzt.
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Metadaten
Titel
Bullöses Pemphigoid – Diagnostik und Therapie
verfasst von
Dr. med. Andrea Kneisel
Prof. Dr. med. Michael Hertl
Publikationsdatum
01.09.2014
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 17-18/2014
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-014-0294-9

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